Re: More on Oxidation – the primary cause for AIDS and “HIV” 7 February 2005
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James J Whitehead,
researcher getting better
40A Josephine Avenue london SW2 2LA

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Re: Re: More on Oxidation – the primary cause for AIDS and “HIV”

Dear Eleni,The Perth Group, Nicholas Bennett,

In Reply to:

"The statement regarding malnutrition is rather contradictory. He admits that malnutrition leads to a “reduced intake of antioxidants. Doesn’t it follow that this will lead to oxidation?

Would Nicholas Bennett explain what he means by the term “stressors” and why they and not the lack of antioxidants are the cause of the oxidation?"

Targeting antioxidant status could help victims of malnutrition

September 20, 2002 Citation: BADALOO,A., REID,M., FORRESTER,T., HEIRD,W.C., Jahoor,f. ., Cysteine Supplementation Improves The Erythrocyte Glutathione Synthesis Rate In Children With Severe Edematous Malnutrition, American Journal Of Clinical Nutrition. 2002. V. 76(3). P. 646-652.

Which can be read by going here:

"Plasma levels of vitamin E (Vit E), polyunsaturated fatty acids of phospholipids (PUFA-PL), lipoperoxides as well as erythrocytes glutathione peroxidase activity (GSH-Px), were evaluated in 200 migrants coming from developing countries, some of which at high risk for serious infective diseases. HIV-1 and syphilis infections were also investigated. 114 subjects (57%) had blood levels of Vit E, PUFA-PL and GSH-Px significantly lower (p less than 0.001, p less than 0.01) than those of normal healthy individuals (n = 30), while lipoperoxides values were unchanged. 8 from this group were found to be HIV-1 positive, and 5 TPHA positive. In contrast, the remaining 86 migrants did not show any signs of infections and their blood parameters were normal enough. These results show that factors such as widespread poverty, inadequate housing, malnutrition, insufficient access to medical care, psychological stress are strictly correlated to the reduction of blood parameters which are critical for the normal cell function of mammalian cells. PUFA-PL deficiency may cause lesions likely due to faulty cellular membranes. The lack of Vit E and GSH -Px, which are considered major protective molecules against lipoperoxidation damage in vivo, has been involved in several human diseases. We suggest that low blood levels of Vit E, GSH-Px and particularly PUFA-PL may play a pathogenetic role in the onset and development of AIDS and other infections. In this connection, we have found that a deficiency of these blood parameters occurs in patients with AIDS (n = 50) and in 32% of HIV seronegative intravenous drug abusers (n = 100). "

Sent: 17/09/2004 00:29 [Blood levels of vitamin E, polyunsaturated fatty acids of phospholipids, lipoperoxides, glutathione peroxidase activity and serological screening for syphilis and HIV in immigrants from developing countries]

[Article in Italian] G Ital Dermatol Venereol. 1990 Nov;125(11):487-91.

Passi S, Morrone A, Picardo M, De Luca C, Bartoli F, Zurlo A, Ippolito F.

Istituto Dermatologico San Gallicano, Roma. To read this artical and others that show that cocaine induces oxidative stress, depletes glutathion ,causes cell death and magnifies hiv IE Activates HIV 1X 200, causes a rise in cortisol and significantley reduces CD4.

Also there are studies there that show that Morthine/herion depletes glutathione, causes oxidative stress, cell death,and cultures/activates x hiv ?.

I must say I found Nicolas Bennett comments on hyper sensitivity to UV radiation in vivo in animals and humans with low GSH not applicable in such circumstances infact the exact reverse is true references available .

I wonder if Nicholas has references for his comments that are applicable to people /animals with high oxidative stress and low/depleted levels of GSH and antioxidants when exposed to radiation or other oxidising factors/agents ? In reply to:

"Nicholas Bennett wrote: “I see no evidence therefore that AIDS patients are exposed to cellular oxidizing agents above and beyond non- AIDS patients.”

There is lots of evidence Nicholas what you state above iss poppycock and grossley untrue and further more theres also evidence that shows people/animals exposed to oxidising factors/agents who have low levels of GSH and antioxidant levels are far more vulnerable to the negative effects of exposure oxidative stress. (Your own recent references demonstrate this)

There are lots of other things I would like to debate regarding this area which I will hopefully post soon.Been out of communication reach recentley.

Would Nicolas Bennett please answer the following simple questions.

1.Does Nicolas still deny/disagree that AZT is oxidative and depletes glutathione ?

2.Does Nicolas still deny/disagree that oxidative stress induces cell death especially and more so in pre GSH and antioxidant depleted/defienct humans and animals ?

3.Does Nicolas still deny/disagree that wasting is predictive of disease and death ?

Best Wishes

James J Whitehead

Clinical trials volunteer

Member and

Competing interests: Member Clinical trials volunteer