Re: "HIV" "a necessary or sufficient cause" for AIDS? 30 September 2004
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Peter J Flegg,
Physician
Blackpool, UK FY3 8NR

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Re: Re: "HIV" "a necessary or sufficient cause" for AIDS?

Christopher Noble wrote: "The increased risk of PCP with HIV infection is so high that if somebody is diagnosed with PCP then we can predict with a high degree of certainty that that person is infected with HIV and is immune suppressed. Hence PCP can be used as an AIDS indicator disease."

The Perth Group dispute this statement, giving some references to show PCP can occur in the absence of HIV infection. The first of these describes cases diagnosed before AIDS was even described and 5 years before a test for HIV was developed. (I wonder how the Perth Group decide none of them had HIV?)

The remainder of the references merely confirm one thing: If you see any cases of PCP in the absence of HIV infection, write them up for journal publication quickly, since they are extremely unusual! I thank the Perth Group for their help in demonstrating the rarity of non-HIV PCP, and confirming Chris Noble's views.

Competing interests: None declared