Re: HIV Tunnel Vision 19 July 2004
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James J Whitehead,
member www.altheal.com
40A josephine Avenue, London SW2 2 LA

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Re: Re: HIV Tunnel Vision

Dear Editor, John Kirkham and I Wrote this link below for a sampling of the evidence that oxidative stress is required for the pathogenesis of AIDS but the significance of this is played down in deference to the HIV hypothesis and the AIDS industry drugs. http://www.altheal.org/texts/oxidative.htm

Volume 351:23-32 July 1, 2004 Number 1

edition of The New England Journal of Medicine reports :A Randomized Trial of Multivitamin Supplements and HIV Disease Progression and Mortality.Which can be reached at http://content.nejm.org/cgi/content/full/351/1/23?query=TOC

Here are some very relevant quotes.

"Conclusions Multivitamin supplements delay the progression of HIV disease and provide an effective, low-cost means of delaying the initiation of antiretroviral therapy in HIV-infected women"

"In addition to enhancing immunity, multivitamins may also reduce HIV replication, as indicated by the significant reduction in viral load. HIV replication in vitro is increased by oxidative stress.27".

{Note reference 27 and NAC}.

"Components of our multivitamin supplement, particularly vitamins C and E, are potent antioxidants.Components of our multivitamin supplement, particularly vitamins C and E, are potent antioxidants. In a small, randomized, placebo-controlled study of 49 HIV-positive patients, those who received daily supplements of both vitamin E (800 IU) and vitamin C (1000 mg) for three months had a significant reduction in lipid peroxidation (a measure of oxidative stress), with a trend toward a reduced viral load.28 ".

The editorial of the New England Journal of Medicine

http://content.nejm.org/cgi/content/full/351/1/78

States along with many other interesting thoughts,

"Fawzi and colleagues' study of multivitamin supplementation should stimulate broader discussion of the role of nutrition in patients with AIDS in the developing world. With its effects on morbidity, mortality, and poverty, the epidemic of HIV infection and AIDS has worsened food security in Africa, especially in the southern part of the continent, the area most affected by HIV. HIV disease increases metabolic requirements, suppresses appetite, may impair swallowing by causing oral and esophageal opportunistic infections, may be associated with malabsorption due to various gastroenteropathies, and perhaps most important, results in progressive disability and impoverishment, with a consequent inability to raise or afford food. Undernutrition also interacts with HIV in a variety of ways. Undernutrition may promote HIV transmission, for example, when sex is exchanged for money to buy food for oneself and one's family. The clinical picture of the HIV wasting syndrome (also known as the "slim disease"), a characteristic manifestation of AIDS in Africa, results in large part from undernutrition in the face of opportunistic illnesses, especially tuberculosis, which itself may be made more likely by inadequate food intake.8,9 Whatever its cause, a reduced body-mass index is a strong predictor of death."

John Kirkham and I refer to this in our paper and body-mass index is still today a strong and independant predictor of mortality in the West as WELL as in Africa even with an "undectectable" "viral-load"}.

Most interestingly the editor states: "Individual, small clinical trials rarely form an adequate basis for policy formulation, and they are unlikely to answer convincingly the important questions now raised specifically, whether multivitamin supplementation can reduce mortality in the context of increased access to antiretroviral-drug therapy and whether the initiation of such therapy can be delayed. These critical questions could potentially be answered in Africa by a so-called large, simple trial.7 "

Altheal has volunteers for clinnical trials into non toxic antioxidant/multivitimins in Africa, USA, Canada, Norway, England, France, Germany and others by hiv so-called symptomatic and hiv so called symptomatic/aids.

Since these treatment approaches have been proposed far more better than I by others at www.theperthgroup.com and www.robertogiraldo.com

Why some 2 decades later are we just starting to look at oxidative stress and nutrician as a means to prevent many pathologies including wasting,TB and the other 20 or so diseases that are sometimes called aids.

One wonders what effects other combinations of antioxidants like foe exampleNAC, S-Acetyl-_Glutathione,Selenium, Vit -c, Vit- E, acetyyl l- carnitine ect, micro nutrients, Amino Acids , Omega 3 and 6 acids, nutrician,avoidance of oxidises and drugs,the treatment and prevent of diseases, good balanced nutrition may have ?

I invite informed polite debate about this, is oxidative stress pivatol to hiv expression and "progression" from hiv to aids ?

Is anyone arguing it is not ?

If Not, Why are we not as The Perth Group proposed some 16 years ago Targeting Oxidative stress itself ?

Again I appeal for informed debate on these matters incuding the contraversial finding of this study about the use of vit-A.

Again I appeal for co-operative members of the medical profession to assist and respect those directly effected with there informed treatment choices. At the moment Governments,the medical profession are providing no choices despite polite requests. There are points where all sides should be co-operating instead of calling each other silly names.

I thankyou for your attention and freedom of thought hopefully the next www.altheal.org conference which will concentrate these very matters will be better attended by both sides since there are members of altheal and the public that are looking at these matters both on and of with and without ARV treatment and there are many areas of agreement.

More research on oxidative stress some 200 to 300 studies,references, interviews with people like Luc Montaignier the discover of hiv can be found among the many notes made by me under the post heading SWEET TASTING MEDICINE THAT WORKS we can be reached on http://forums.delphiforums.com/innocuous/start

Best Wishes ( Dont waste more time and human lives and give people a choice, lets have polite informed debate )

James J Whitehead

Competing interests: Long term Survivor of hiv/oxidative stress/aids Researcher Continuum Magazine,Member of www.altheal.com