Re: A simple question for Brian T Foley 24 March 2004
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Brian T Foley,
HIV Researcher
Los Alamos National Lab, Los Alamos, NM 87545

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Re: Re: A simple question for Brian T Foley

Anita Allen writes:
"...yet no search of the Internet throws up any research by him. "

Apparently Ms. Allen is not very adept at searching the Internet. One can use http://www.google.com to search for "Brian Foley AIDS HIV" and find a few things I have written. But most of my work has been in peer-reviewed publications that can be found with a PubMed/MedLine search at http://www.ncbi.nlm.nih.gov/

1: Sung H, Foley BT, Ahn SH, Kim YB, Chae JD, Shin YO, Kang HI, Cho YK.
Natural polymorphisms of protease in protease inhibitor-naive HIV-1 infected patients in Korea: a novel L63M in subtype B.
AIDS Res Hum Retroviruses. 2003 Jun;19(6):525-30.
2: Hu J, Switzer WM, Foley BT, Robertson DL, Goeken RM, Korber BT, Hirsch VM, Beer BE.
Characterization and comparison of recombinant simian immunodeficiency virus from drill (Mandrillus leucophaeus) and mandrill (Mandrillus sphinx) isolates.
J Virol. 2003 Apr;77(8):4867-80.
3: Mokili JL, Rogers M, Carr JK, Simmonds P, Bopopi JM, Foley BT, Korber BT, Birx DL, McCutchan FE.
Identification of a novel clade of human immunodeficiency virus type 1 in Democratic Republic of Congo.
AIDS Res Hum Retroviruses. 2002 Jul 20;18(11):817-23.
4: Novitsky V, Smith UR, Gilbert P, McLane MF, Chigwedere P, Williamson C, Ndung'u T, Klein I, Chang SY, Peter T, Thior I, Foley BT, Gaolekwe S, Rybak N, Gaseitsiwe S, Vannberg F, Marlink R, Lee TH, Essex M.
Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design?
J Virol. 2002 Jun;76(11):5435-51.
5: Beer BE, Foley BT, Kuiken CL, Tooze Z, Goeken RM, Brown CR, Hu J, St Claire M, Korber BT, Hirsch VM.
Characterization of novel simian immunodeficiency viruses from red-capped mangabeys from Nigeria (SIVrcmNG409 and -NG411).
J Virol. 2001 Dec;75(24):12014-27.
6: Sung H, Foley BT, Bae IG, Chi HS, Cho YK.
Phylogenetic analysis of reverse transcriptase in antiretroviral drug-naive Korean HIV type 1 patients.
AIDS Res Hum Retroviruses. 2001 Nov 1;17(16):1549-54.
7: Novitsky V, Rybak N, McLane MF, Gilbert P, Chigwedere P, Klein I, Gaolekwe S, Chang SY, Peter T, Thior I, Ndung'u T, Vannberg F, Foley BT, Marlink R, Lee TH, Essex M.
Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design.
J Virol. 2001 Oct;75(19):9210-28.
8: Gao F, Trask SA, Hui H, Mamaeva O, Chen Y, Theodore TS, Foley BT, Korber BT, Shaw GM, Hahn BH.
Molecular characterization of a highly divergent HIV type 1 isolate obtained early in the AIDS epidemic from the Democratic Republic of Congo.
AIDS Res Hum Retroviruses. 2001 Aug 10;17(12):1217-22.
9: Novitsky VA, Gaolekwe S, McLane MF, Ndung'u TP, Foley BT, Vannberg F, Marlink R, Essex M.
HIV type 1 A/J recombinant with a pronounced pol gene mosaicism.
AIDS Res Hum Retroviruses. 2000 Jul 1;16(10):1015-20.
10: Novitsky VA, Montano MA, McLane MF, Renjifo B, Vannberg F, Foley BT, Ndung'u TP, Rahman M, Makhema MJ, Marlink R, Essex M.
Molecular cloning and phylogenetic analysis of human immunodeficiency virus type 1 subtype C: a set of 23 full-length clones from Botswana.
J Virol. 1999 May;73(5):4427-32.
11: Se-Thoe SY, Foley BT, Chan SY, Lin RV, Oh HM, Ling AE, Chew SK, Snodgrass I, Sng JE.
Analysis of sequence diversity in the C2-V3 regions of the external glycoproteins of HIV type 1 in Singapore.
AIDS Res Hum Retroviruses. 1998 Nov 20;14(17):1601-4.

Anita writes:

"Could Foley please supply the relevant information as to where one can find the information that any test is approved by the FDA to diagnose “HIV infection” and which test by manufacturer name and title that would be? It’s a simple question and it requires a short at most two-line answer. No obfuscations and no explanations will be needed, please Dr Foley. "

because of course she is well aware that no single test is used for full "diagnosis" of HIV infection. The FDA (and the governing bodies of most developed countries) require at least 2 different tests for full diagnosis. In the USA an EIA or ELISA must be followed up by a western blot. In some countries, two different EIA or ELISA tests can be used.

See for example:
http://www.fda.gov/cber/pmasumm/P010047S.pdf
Paul SM, Grimes-Dennis J, Burr CK, DiFerdinando GT.
Rapid diagnostic testing for HIV. Clinical implications.
N J Med. 2003 Sep;100(9 Suppl):11-4; quiz 63-4. Review.

Competing interests: None declared