Re: Finding wood among the trees 25 September 2003
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Brian T Foley,
HIV Researcher
Los Alamos National Lab, Los Alamos, NM USA 87545

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Re: Re: Finding wood among the trees

The Perth Group wrote:
Quote ..."
“You have claimed: "By comparison, two RNA containing viruses (polio and influenza, the latter after 27 years of dormancy,) vary by less than 1%" “

We have performed a search of all the rapid responses and could not find this quote attributed to us (apart from the two rapid responses of Christopher Noble).
..." end quote.

The exact statement made by Chris Noble can't be found because he was paraphrasing what the Perth Group said above:
Quote ..."
The difference between the sequences of the chimpanzee genome and the human genome is less than 2%, while the genomes of RNA viruses do not differ by more than 1% and even this 1% sequence differences are considered to represent "extreme variability". (9)

For example, “The type 3 Sabin poliovirus vaccine differed from its neurovirulent progenitor at only 10 nucleotide positions after 53 in vitro and 21 in vivo passages in monkey tissues. In 1977, H1N1 influenza A virus reappeared in the human population after 27 years of dormancy with sequences mainly identical to those of the 1950s virus".
..." end quote

I find it ironic that the Perth Group is interested in genetic sequences of certain strains of polio, influenza and other viruses, but not at all interested in genetic sequences of lentiviruses. None of these viruses has ever been "isolated" by the Perth Group's impossible criteria. In fact no virus has ever been isolated by those criteria. This leaves me curious as to why the Perth Group has picked out the Human Immunodeficiency Viruses as the only viruses to attack in their commentary.

Competing interests:   None declared