Re: Re: Re: A plea to Eleni Papadopulos-Eleopulos 20 August 2003
Previous Rapid Response Next Rapid Response Top
Jeffrey L Evans,
None
Redstone

Send response to journal:
Re: Re: Re: Re: A plea to Eleni Papadopulos-Eleopulos

It seems like old times. I have come to accept that there is no combination of words in the English language which is safe from semantic objection. If the word "insert" is too broad a term for your liking, I would appreciate your assistance in replacing it with another which would adequately express what I feel to be a very important distinction between HPV and HIV, as described below.

The role of human papillomaviruses in human cancers

In general, HPV-associated cancers arise from a single accidental integration event of the viral genome into a host cell chromosome. Integration is a terminal event for the viral life cycle. Munger K. Front Biosci. 2002 Mar 1;7:d641-9.

HIV-1 integration as a target for antiretroviral therapy: a review

During HIV replication, the integration of the genome into the cellular chromosome is a vital step, which is catalysed by the viral integrase. Pluymers W, De Clercq E, Debyser Z Curr Drug Targets Infect Disord. 2001 Aug;1(2):133-4

Competing interests:   None declared