If It's Good Enough for RSV, Then It is Good Enough for HIV. 24 June 2003
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Tony Floyd,
Medical Student
Newcastle University

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Re: If It's Good Enough for RSV, Then It is Good Enough for HIV.

It has been posited above that:

>an individual positive in New York City on the CDC criteria would not be positive in Sydney, Australia.

How extraordinary. Is there even one patient that you are aware of that this theory would apply to?

Is there anyone who, confirmed positive by all tests in New York, would then not be positive by the usual series of tests in Sydney?

Or is it just a one-in-a-million hypothetical?

In which case it deserves as much attention as the plethora of other alternative AIDS arguments.

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The attempted side-step of Brian Foley's question deserves attention:

What he asked was:

> If the Perth group believes that their method is valid for studying viruses, they should be able to name at least one virus which has been studied using their criteria. Where is the evidence that ANY virus has EVER been "purified" to their satisfaction?

This was in no way satisfied by merely providing references to a paper from 1961 about the Rous Sarcoma Virus and from 1973 about the Murine Sarcoma Virus.

No indication was given as to why the papers might support the use of Density Gradient Centrifugation as a valid means of proving the existence any virus these days?

Why have even the two little known viruses mentioned not been associated with this separation technique in the last 30 years?

If you did cite the 1961 paper on Rous Sarcoma Virus as an example of a virus purified to your satisfaction, is it not ironic that RSV is a retrovirus very similar to HIV? In fact the fusion protein and an envelope glycoprotein precursor have been shown to be similar in both viruses(1)

If you are satisfied about the purification of RSV, then why is HIV so different?

Do you except that there might be a chance that all the infectious disease experts, virologists and vaccine developers around the world are working with a very real virus called HIV?

References:

(1) Streckert HJ, Werchau H. Epitopes at the proteolytic cleavage sites of HIV-1-gp120 and RSV-F protein share a sequence homology: comparative studies with virus-induced and antipeptide antibodies. Intervirology. 1992;34(1):30-7. PMID: 1385356

Competing interests:   None declared